Joselyn Soto
assistant professor
Degrees
PhD, Neuroscience, University of California Los Angeles (UCLA)
BS, Cell and Molecular Biology, University of California Riverside (UCR)
Research Areas
Cellular and molecular neuroscience, astrocyte biology, glial biology, cell-specific signaling pathways, astrocyte-neuron interactions
Courses Regularly Taught
Intermediate Cell Biology, Cellular and Molecular Biology
Publications
Soto JS, Neupane C, Kaur M, Pandey V, Wohlschlegel JA, Khakh BS. (2024) Astrocyte Gi-GPCR signaling corrects compulsive-like grooming and anxiety-related behaviors in Sapap3 knockout mice. Neuron, (Epub ahead of print) doi: 10.1016/j.neuron.2024.07.019.
Ollivier M, Soto JS, Linker KE, Moye SL, Jami-Alahmadi Y, Jones AE, Divakaruni AS, Kawaguchi R, Wohlschlegel JA, Khakh BS. (2024) Crym-positive striatal astrocytes gate perseverative behaviour. Nature, 627(8003):358-366. doi: 10.1038/s41586-024-07138-0.
Soto JS, Jami-Alahmadi Y, Wohlschlegel JA, Khakh BS. (2024) In vivo identification of astrocyte and neuron subproteomes by proximity-dependent biotinylation. Nature Protocols, 19(3):896-927. doi: 10.1038/s41596-023-00923-7
Soto JS, Jami-Alahmadi Y, Chacon J, Moye SL, Diaz-Castro B, Wohlschlegel JA, Khakh BS. (2023) Astrocyte-neuron subproteomes and obsessive-compulsive disorder mechanisms. Nature, 616(7958):764-773. doi: 10.1038/s41586-023-05927-7
Gangwani MR, Soto JS, Jami-Alahmadi Y, Tiwari S, Kawaguchi R, Wohlschlegel JA, Khakh BS. (2023) Neuronal and astrocytic contributions to Huntington's disease dissected with zinc finger protein transcriptional repressors. Cell Reports, 42(1):111953. doi: 10.1016/j.celrep.2022.111953
Endo F, Kasai A, Soto JS, Yu X, Qu Z, Hashimoto H, Gradinaru V, Kawaguchi R, Khakh BS. (2022) Molecular basis of astrocyte diversity and morphology across the CNS in health and disease. Science, 4;378(6619):eadc9020. doi: 10.1126/science.adc9020.
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