Picture of Dr. Saco

Contact Information

Office: MH 685A

Phone: 657-278-2539


Melanie A. Sacco

associate Professor


PhD, University of London

MS, University of Western Ontario

BS, University of Western Ontario

Research Areas

Molecular biology of plant-pathogen interactions, protein-protein interactions and signaling in disease resistance, avian endogenous retroviruses

Courses Regularly Taught

Genetics and Molecular Biology, Plant Molecular Biology, Molecular Virology, Principles of Gene Manipulation


Wang, K.-D., Empleo, R., Nguyen, T. T. V., Moffett, P. and Sacco, M. A. (2015) Elicitation of Hypersensitive Responses in Nicotiana glutinosa by the Suppressor of RNA Silencing Protein P0 from Poleroviruses.Molecular Plant Pathology 16,435-48.

Sobhanian, S. and Sacco, M. A. (2014) Divergent evolution of potato immune receptor CC domain interactions with the Ran GTPase-activating protein 2. Plant Signaling & Behavior. 9,e29772.

Sacco, M. A. and Venugopal K. Nair (2014) Prototype EAV Endogenous Retroviruses of the Gallus Genus. Journal of General Virology doi:10.1099/vir.0.066852-0

Sacco, M. A. , Koropacka, K., Grenier, E., Jaubert, M., Blanchard, A. Goverse, A., Smant, G. & Moffett, P. (2009) The Cyst Nematode SPRYSEC Protein RBP-1 Elicits Gpa2- and RanGAP2-Dependent Plant Cell Death PLoS Pathogens 5, e1000564. doi:10.1371/journal.ppat.1000564. http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1000564 Opens in new window

Sacco, M. A. , Mansoor, S. & P. Moffett. (2007) A RanGAP protein physically interacts with the NB-LRR protein Rx and is required for Rx-mediated viral resistance. The Plant Journal 52, 82-93.  http://onlinelibrary.wiley.com/doi/10.1111/j.1365-313X.2007.03213.x/abstractOpens in new window