IRB Basic Steps

How to submit a protocol USing Cayuse irb

CSUF IRB has upgraded to Cayuse Institutional Review Board (IRB) system for online submission and processing of human subject research studies (protocols) in accordance with CSU, federal, ethical, and regulatory standards.

The Cayuse IRB module is an easy-to-use system for electronically preparing, submitting, and routing studies for IRB approval. All information is stored in the cloud and can be accessed securely from any location, making it simple for multiple simultaneous users to view and share documents. Users receive electronic notifications whenever an action is required on their part, allowing the study to proceed smoothly through each step of the process from study creation to final approval.

Step-by-step instructions on how to  create an Initial Submission can be reviewed in the following PDF document:
Cayuse IRB Protocol Submission (User Guidelines)PDF File Opens in new window

For additional guidance on how to address reviewer feedback, access the step-by-step instructions for Cayuse IRB: Addressing Primary Reviewer CommentsPDF File Opens in new window .

In addition, the video tutorial below will guide users through the step-by-step process outlining the entire IRB Cayuse application : User - How to Complete a Cayuse IRB Application (41:07)Opens in new window


Or click below to reference a specific section of the application.

  • 0:00 - Creating an application

  • 1:21 - Introduction

  • 10:28 - Funding Information

  • 12:49 - Project Description

  • 15:19 - Participant Information

  • 20:12 - Data Collection

  • 27:25 - Risk and Benefits

  • 29:55 - Informed Consent Process

  • 33:34 - Anonymity and Confidentiality

  • 36:51 - Subject Matter

  • 37:18 - Debriefing

  • 37:49 - Conflict of Interest

  • 39:25 - Submitting and Certifying the Application

  • 40:48 - Questions or Concerns


*Cayuse IRB runs on Internet Explorer 9 or higher, Mozilla Firefox, Google Chrome, or Apple Safari.